Text Box: Estriol is the weakest of the three estrogens.  Estriol studies have shown that apparently it has a lower risk for breast cancer.  They have also shown that it possibly may have a protective effect on the breasts.  Unlike conjugated estrogens or estradiol, when estriol is taken, it is not converted into estrone.   This means that you aren’t exposing yourself to the estrogens that have been linked to cancer.

The studies on estriol are one of the main reasons that more researchers are trying to find a way to use estriol alone as an estrogen replacement.  This would be used in place of the commonly prescribed conjugated estrogens or estradiols that are being used now.
The importance and benefits of estriol is its weakness.  It Text Box: seems that estriol offers the benefits of the stronger estrogens, with much fewer side effects and risks.   Tests that have been completed have shown that estriol relieves menopausal symptoms, and protects against heart disease and osteoporosis.  The other estrogens do the same, but estriol doesn’t appear to increase the risk of breast cancer or endometrial cancer.  Actually, many studies have indicated that estriol has an anti-cancer effect, and actually may work better than tamoxifen for women with breast cancer.  In addition, studies have also found that estriol seemed to be a better choice for women who have had troubles tolerating the stronger estrogens.
Along with the weakness of estriol being a positive, it is also a negative.  Since it is Text Box: much weaker than the other estrogens, a much higher dose is needed for it to take effect.  A high dose can cause nausea, as estriol is the estrogen that rises with pregnancy, often causing morning sickness.
Currently, estriol is not a widely prescribed drug due to the fact there isn’t a current patent on it and no pharmaceutical companies have put a name to it.  Hopefully with increasing research and information, there will be an increase in the usage within the next few years.

Source:
Nov. 30, 2005.  http://www.earlymenopause.com/hrt_estriol.htm.  Copyright © 1999-2005 EarlyMenopause.com, All Rights Reserved. 

Text Box: valuable information. It's important not to lose sight of that."
But many scientists worry that the recent findings will leave the public unconcerned about diet and other lifestyle choices, which are very important to the overall benefits of hormone therapy, and thus, leaving the government hesitant to fund research.
"If the public and legislators come away saying, 'Oh, we can never get an answer from these scientists. It's useless to spend money testing diet' -- then a lot of damage will have been done," said Meir Stampfer of the Harvard School of Public Health. "Nutrition is important. We've already learned a lot that offers people plenty of sound advice. But there is a lot more Text Box: "Women are being flooded with a lot of information from these studies," said Sherry Marts of the Society for Women's Health Research. "The challenge is trying to put this rush of information in context."
Many researchers emphasized the fact that the Women’s Health Initiative Study was in many ways very well conceived, designed and executed, and has produced valuable information.  The most important aspect of their findings was the warning it gave older menopausal women about the dangers of long-term hormone therapy.
"It's the most important trial of the century," said Adriane-Fugh-Berman of Georgetown University School of Medicine. "It gave us scads of incredibly Text Box: we can learn. We just have to approach it in a smarter way."
The confusion, unclear results, and the wrong turns that have become clear only in hindsight, have left many researchers chastened about attempting such ambitious projects in the future.
"It's very sobering," Byers said. "What it says for the future is that when we do studies, especially studies that are big and expensive and long, we have to make sure we are testing the right interventions and testing them the right way. That can be a lot harder than it seems."
Source:
http://www.msnbc.msn.com/id/11435731/.  © 2006 MSNBC.com.

Text Box: Bioidentical Estriol: The Better Estrogen in Protecting Against Breast Cancer    

 By: Megan Mathews
Text Box: “Early menopause is something that has happened to many women, and there are things you can do to help make this time easier on you and your body.”

Page        Bioidentical Hormones: The Hormone Information you’ve been Looking for     Volume 1, Issue 3

It’s Important to know your health risks ahead of time.  The best method of treatment is early detection and prevention.  Knowing you family history can be a huge factor when it comes to preventing certain diseases.

Copyright 2005-2006 Bioidentical Medical Dictionary

Disclaimer
The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. The content provided is intended strictly for informational purposes to help patient understanding of medical terms and conditions.

Text Box: Confusion over Study Results Leave Women Guessing
By:  Megan Mathews